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[Correspondence] Optical coherence tomography-guided PCI

I read with great interest the results of the ILUMIEN III trial by Ziad Ali and colleagues (Nov 26, p 2618–28),1 which did not show superiority for optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) compared with angiography-guided PCI. No difference was found in the primary endpoint—minimum stent area after PCI—between the two strategies (p=0·12). Although guidance by OCT resulted in fewer untreated dissections than did guidance by angiography (39 vs 61, p=0·006), this difference was driven by an increase in the number of minor dissections in the angiography group compared with the OCT group (35 vs 20, p=0·02); there was no difference in the number of major dissections between the groups (p=0·25).

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