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[Correspondence] Preconception health – Authors’ reply

We thank Lombarte and colleagues for their supportive comments and interesting data on calcium diet in rats, and look forward to the results of their randomised trial. A crucial theme of the second paper1 in our Series was that the origin of adverse offspring phenotype could be traced to periconceptional diet or environmental exposure, hence the need for preconception health. However, we note that in the calcium study2 by Bergel and Belizán in rats, experimental diets lasted for one month before mating to the end of pregnancy; therefore the effects on offspring blood pressure might derive from a broad period of exposure.