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[Correspondence] Preventing bloodstream infection in children: What’s the CATCH? – Authors’ reply

Sara Boyd and colleagues call for further research into antibiotic resistance before widespread adoption of antibiotic-impregnated central venous catheters for children. We agree that the evidence on selection of resistant organisms does not disprove the possibility that, in certain circumstances, antibiotic-impregnated central venous catheters can select resistant organisms. Over the past 20 years, evidence from in-vitro studies,1 controlled trials, and long-term surveillance of rifampicin-minocycline central venous catheters in adult patients2 has suggested that the risks are small.

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