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[Correspondence] Prolonged glucocorticoid treatment in acute respiratory distress syndrome – Authors’ reply

G Umberto Meduri and Reed A C Siemieniuk incorrectly suggest our Seminar1 misinterprets the literature regarding corticosteroids in acute respiratory distress syndrome. Although more recent studies might have refined the research question, older studies still remain the best evidence to address the question such studies originally asked, and so are not outdated. These older studies are the reason high-dose steroids are not used today.