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[Correspondence] Prophylactic antibiotics to reduce pneumonia after acute stroke – Author’s reply

Ioan Milosevic and colleagues pointed out that the outcomes presented in our Article1 were different from those in the ISRCTN registry (number ISRCTN37118456). They stated that one pre-specified primary outcome (“hospital costs”) was not reported, and a new co-primary outcome (“physician diagnosed post-stroke pneumonia”) added. We have clarified in the Methods section that physician diagnosed pneumonia was not a primary outcome but was presented as an alternative to algorithm-based diagnosis to harmonise with diagnostic criteria used in previous studies.

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