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[Correspondence] Renal denervation for resistant hypertension – Authors’ reply

We thank Miryana Mircheva and colleagues for their letter about the DENERHTN study.1 They noted the consistency of the ambulatory and office blood pressure decrease in our study.1 This agreement reflects the quality of the standardisation of blood pressure measurements as shown by the remarkably small differences between office and daytime ambulatory systolic/diastolic blood pressure values at randomisation (–4·5/0·1 mm Hg),1 by contrast with those of Symplicity HTN-3 (–16·7/–5·2 mm Hg).2 This is consistent with our previous trial in patients with resistant hypertension, in which the difference from baseline to 6 months in ambulatory and office blood pressure levels between two different treatment strategies was similar.