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[Correspondence] Safety and efficacy of statins

Rory Collins and colleagues1 conclude that statins do not cause muscle complaints without marked increases in concentrations of creatine kinase because such symptoms are not observed in randomised controlled clinical trials (RCTs). They suggest that such symptoms are imagined or misattributed by patients who have been warned about possible muscle complaints. The STOMP trial2 was designed to examine muscle complaints in patients assigned to atorvastatin 80 mg daily or placebo. Participants were queried bi-weekly about muscle symptoms.

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