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[Correspondence] Safety and efficacy of statins

The 2016 Review by Rory Collins and colleagues (Nov 19, p 2532),1 of evidence about the efficacy and safety of statin therapy, claims that the 2012 Cholesterol Treatment Trialists’ (CTT) meta-analysis shows that “lowering LDL cholesterol by 2 mmol/L (77 mg/dL) with an effective low-cost statin regimen (eg, atorvastatin 40 mg daily) for 5 years in 10 000 patients would typically prevent major vascular events from occurring in…500 patients (ie, 5% absolute benefit) who are at increased risk but have not yet had a vascular event (primary prevention)”.