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[Correspondence] Simplified antibiotic regimens for neonatal sepsis—AFRINEST

Findings from the AFRINEST trial,1 which took place in three sub-Saharan African countries, have shown that simplified antibiotic regimens (including regimens with only 2 days of parenteral treatment) delivered at home or at primary health-care level are as effective as a parenteral regimen (the current WHO recommendation) for the treatment of severe bacterial infection in newborn babies. If these simplified regimens are implemented at scale, thousands of families that currently do not have access to hospital care will benefit from this intervention.