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[Correspondence] Simplified antibiotic regimens for neonatal sepsis—AFRINEST – Authors’ reply

We thank our colleagues for their remarks on our studies. In the AFRINEST studies,1,2 done in a programme setting, we assessed regimens for outpatient treatment of young infants with clinical signs of severe infection whose families could not comply with advice to admit their child to hospital. Hospital treatment of such infants remains the treatment of choice, and about half of infants with signs of severe infection who were referred to hospital were not the target of this intervention.