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[Correspondence] Sirolimus for systemic lupus erythematosus

We read with great interest the trial of sirolimus done by Zhi-Wei Lai and colleagues (March 24, p 1186).1 There have been few genuine advances in the management of lupus since the 1960s, and although the prospect of a novel, effective treatment is tantalising, we believe it premature to infer any efficacy of sirolimus on the basis of results reported.