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[Correspondence] Sodium and cardiovascular disease

Andrew Mente and colleagues1 ignore a possible source of bias in their analysis of the association of sodium excretion with cardiovascular events. At any measure of blood pressure, the population will comprise individuals with varying extents of sodium sensitivity, and those with higher sensitivity will achieve that blood pressure if they ingest less sodium.2 As a result, within any blood pressure range—for example, normotensive—there will be an anticorrelation between sodium intake and sodium sensitivity.

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