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[Correspondence] Targeted radiotherapy for early breast cancer

We congratulate Charlotte E Coles and colleagues (Sept 9, 2017, p 1048)1 on their randomised trial (IMPORT LOW) ratifying partial-breast irradiation and confirming the original hypothesis2 proposed in The Lancet 20 years ago.3 In 2010, the independent commentary accompanying the first results of the TARGIT-A trial4 of single-dose targeted intraoperative radiotherapy (TARGIT-IORT), published in The Lancet by the authors of this letter, presented partial-breast irradiation as the new standard for suitable patients.