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[Editorial] The final verdict on Paolo Macchiarini: guilty of misconduct

In this issue, we are retracting two papers by Paolo Macchiarini and co-authors after receiving requests to do so from the new President of the Karolinska Institute (KI), Ole Petter Ottersen. In its final decision, the KI finds that the research reported in the 2011 Lancet paper and elements of a Review published in 2012 “constitutes scientific misconduct”. In his request for retraction, Ottersen states that ”no ethical permit had been obtained for the underlying research. The research was carried out without sufficient support by preclinical data, and the paper presents its data in a way that is unduly positive and uncritical.