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Effectiveness of a care bundle to reduce central line-associated bloodstream infections

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Central line-associated bloodstream infections (CLABSIs) are an important source of morbidity, mortality and cost.1 About 4000 CLABSIs occur in Australian intensive care units (ICUs) each year, with an estimated nationwide cost of $36.26 million and a mortality rate of 4%–20%.2,3 The importance placed on CLABSI and its prevention has prompted standardised monitoring for quality assurance and innovation of preventive strategies.1,4,5 Care bundles focused on improving line insertion procedure have proven successful overseas.1,6 Local implementation of a similar care bundle to that used overseas across New South Wales proved successful, and prompted the Australian and New Zealand Intensive Care Society CLABSI Prevention Project.7,8 Despite these interventions, CLABSI rates range from 0.9 to 3.6 per 1000 central line days.6,7,920