Log in with your email address username.

×

Attention doctorportal newsletter subscribers,

After December 2018, we will be moving elements from the doctorportal newsletter to MJA InSight newsletter and rebranding it to Insight+. If you’d like to continue to receive a newsletter covering the latest on research and perspectives in the medical industry, please subscribe to the Insight+ newsletter here.

As of January 2019, we will no longer be sending out the doctorportal email newsletter. The final issue of this newsletter will be distributed on 13 December 2018. Articles from this issue will be available to view online until 31 December 2018.

Long term risk of severe retinopathy in childhood-onset type 1 diabetes: a data linkage study

- Featured Image

The known Microvascular complications in people with type 1 diabetes mellitus are directly related to glycaemic control. 

The new This is the first study to assess the risk of complications in people with type 1 diabetes according to their glycaemic control trajectory between childhood and adulthood. Severe diabetic retinopathy (SDR) was associated with higher paediatric HbA1c levels, independent of glycaemic control during adulthood. Importantly, SDR was not documented in patients with a stable low glycaemic control trajectory. 

The implications Target-based treatment from the time of diagnosis of type 1 diabetes in childhood is required to reduce the risk of SDR during adulthood. 

Whether microvascular complications develop in people with type 1 diabetes mellitus is critically dependent on their glycaemic control.13 In the large Diabetes Control and Complications Trial (DCCT) and the Epidemiology of Diabetes Complications (EDIC) trial, however, mean glycated haemoglobin A1c (HbA1c) levels could only be estimated from data acquired at trial entry; consequently, the effect of the cumulative glycaemic…

email