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[Perspectives] Marcia Stefanick: women’s west coast initiatives lead to wisdom

In a career devoted to rattling the defensive bars of received wisdom, Marcia Stefanick’s restless scrutiny of the status quo has lighted on a new target: human biology. “At this point I feel strongly that some of our basic biology is wrong. It may not be profoundly wrong. It may in some cases just need tweaking. But in other cases I feel it is wrong.” The specific area in which she believes it to be failing is the longstanding neglect of sex differences. “If you look at basic science there’s a predominance of male animals, male rodents.” In the past, much the same was true of many clinical trials and other human research studies.