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[Perspectives] Off the cuff: rebooting blood pressure treatment

The sphygmomanometer was first introduced into clinical practice some 120 years ago, followed decades later by the concept of high blood pressure as a disease. It took several more decades before antihypertensive medications became available, and today there are nearly a dozen individual classes of blood pressure-lowering drugs. Yet despite having the basic tools necessary to diagnose and treat hypertension for over half a century, high blood pressure remains one of the leading contributors to morbidity and mortality worldwide.