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Pre-hospital thrombolysis in ST-segment elevation myocardial infarction: a regional Australian experience

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The known Pre-hospital thrombolysis in patients with ST-segment elevation myocardial infarction (STEMI) has been found to be an effective strategy in randomised controlled trials.

The new Pre-hospital thrombolysis is safe and effective in the real world setting, especially in a region where transport distances to the cardiac catheterisation laboratory are great.

The implications Pre-hospital thrombolysis can be implemented in regions where timely primary percutaneous coronary intervention for STEMI patients is not available.

Primary percutaneous coronary intervention (PCI), if performed in a timely manner, is the preferred reperfusion strategy for patients with an ST-segment elevation myocardial infarction (STEMI).1 However, physicians in regions geographically isolated from a primary PCI centre are unable to perform PCI rapidly, and the optimal reperfusion strategy is therefore undefined. Recent guidelines have highlighted the importance of systems-based approaches to STEMI management, taking into account regional characteristics.2 In Australia, many patients are a long way from a primary PCI centre, and these patients usually receive thrombolysis in hospitals that are not PCI-capable. However, if reperfusion with thrombolysis fails or a contraindication…