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Prescribing trends before and after implementation of an antimicrobial stewardship program

Up to 50% of antimicrobial agents prescribed to hospital inpatients are considered to be inappropriate,1,2 and this excess use has been associated with increased mortality, adverse drug reactions and the development of resistant bacteria.3,4 The Australian Commission on Safety and Quality in Health Care recently published recommendations for hospital-based antimicrobial stewardship programs.2 A variety of approaches are available to implement these recommendations, including dissemination of guidelines, education, restricting antimicrobial availability and postprescribing audit and review.

We aimed to evaluate changes in antimicrobial prescribing after the implementation of an antimicrobial stewardship program in a specialist tertiary referral hospital.



Alfred Health is a health service…